Zavation’s implant integrates a porous architecture with a nano-textured titanium interface.
FLOWOOD, Miss.—Rather than relying on the strengths of a single material, the most advanced cervical interbody implant introduced by Zavation Medical Products, LLC, leverages the complementary benefits of two proven technologies.
Zavation’s Varisync® NanoPrime ALIF Cage with anchors. (Image: Zavation/PRNewswire)
The cervical interbody implant integrates NanoPrime® Titanium Ion Bond Technology with the company’s proprietary Labyrinth® porous PEEK architecture. The combination, according to a press release by Zavation, is “engineered to elevate the mechanical advantages of PEEK with the biological benefits of titanium.”
In November, Zavation introduced NanoPrime with its Varisync® ALIF (anterior lumbar interbody fusion) interbody system, stating in a release that NanoPrime will serve as a platform technology incorporated across the Labyrinth® Porous PEEK interbody offering.
“Zavation believes this will be the first titanium porous PEEK interbody with nanoscale features, truly offering the best attributes of titanium, porosity, and PEEK in one interbody technology,” the release stated.
NanoPrime uses a cutting-edge nano-engineering process that involves evaporation and ion beam bombardment in a high vacuum environment. The technique allows intermixing of coating and substrate atoms, improving adhesion and minimizing risk of delamination, unlike conventional coatings, the company said in the release.
NanoPrime, a nano-textured titanium ion bond surface, is reported to create a high-adhesion, nano-textured surface that has been shown to support cellular activity associated with bone formation. Labyrinth, Zavation’s patented porous PEEK structure, is designed to mimic cancellous bone architecture and improve the biological response compared to smooth PEEK or traditional solid structures, according to the release.
Combined, these technologies are reported to “deliver an implant platform that maintains the imaging clarity and elastic modulus of PEEK while introducing an osteoconductive nano-surface intended to promote early cell attachment, induce hydrophilic wicking, and reduce stress shielding.”
A fellowship-trained spine surgeon, Freeland Ackley, specializes in degenerative, revision, and minimally invasive spine procedures for the comprehensive treatment of cervical, thoracic, and lumbar conditions.
“The NanoPrime® Labyrinth® Cervical Interbody reflects the kind of design philosophy I look for in an implant—thoughtful engineering that supports early bone integration and long-term stability,” Ackley stated in the release. “The combination of porous architecture with a nano-textured titanium interface gives me confidence in the construct I’m using in my practice.”
Zavation’s NanoPrime® Labyrinth® Cervical Interbody is engineered to bring the mechanical advantages of PEEK to the fore, along with the biological benefits of titanium. (Image: Zavation/PRNewswire)
A cohesive biological environment—inside and out
By applying NanoPrime to the porous Labyrinth structure, Zavation has created what it describes as “a fully integrated surface environment—from the macro-porous architecture to the nano-textured titanium interface.” This synergy is engineered to encourage bony integration throughout the porous network and promote osteogenic cellular behavior associated with accelerated fusion, according to the release. It is also said to be engineered to “maintain mechanical properties and visualization advantages valued by surgeons,” and to “provide a predictable, uniform surface across the entire implant geometry.”
“The NanoPrime® Labyrinth® Cervical interbody represents the next step in strengthening our platform of interbody materials and structures, giving distributors and surgeons greater design and stiffness modalities,” said Derek Kuyper, chief executive officer of Zavation, in a statement. “By integrating NanoPrime® and Labyrinth® technologies into our cervical line, we’re offering a world-first interbody cage with the macro, micro, and nano level features of 3D titanium with the imaging characteristics and device stiffness of PEEK, the best of both in one device.”
Zavation is an employee-owned designer and manufacturer of spinal hardware and biologics headquartered in Flowood, Mississippi.